Effect of cholecalciferol on unsaturated model membranes

Vitamin D plays an important role in many physiological processes, particularly calcium and phosphorous homeostasis. The biochemistry of vitamin is also complex, encompassing a range active molecules that may be either endogenous or dietary origin. lipids fats the production, processing use interesting one, with relative paucity model studies into interactions lipidic systems such as micelles vesicles. Here, we have studied effect D3 simple unsaturated phospholipid systems. We used NMR FTIR spectroscopy to investigate increasing concentration on structure dynamics lipid chains interfacial region. In order link these more complex biomimetic environments, compare results presence buffer binding protein. DLS determine D3-DOPC vesicles can retain their size distribution for varying amounts time different conditions. find acyl chain region membranes are generally disordered, addition and/or protein alters properties